Tylenol Cold + Flu Severe Day/Night Caplets provide temporary relief of cold and flu symptoms. The daytime caplets are formulated to loosen phlegm and temporarily relieve symptoms such as headache, sore throat, nasal congestion and cough. The Nighttime caplets help relieve runny nose and sneezing along with other symptoms such as headache, cough, sore throat, nasal congestion, sinus congestion and pressure. Both formulas also temporarily reduce fever, for relief any time of the day. This convenient combo pack contains 24 caplets with 16 Daytime caplets and 8 Nighttime caplets. Each medicine caplet contains 325 mg of acetaminophen, a pain reliever and fever reducer; 5 mg of phenylephrine HCl, a nasal decongestant; and 10 mg of dextromethorphan HBr, a cough suppressant. The Daytime caplets also contain guaifenesin 200 mg, an expectorant to help loosen phlegm (mucus), while the Nighttime caplets contain chlorpheniramine maleate 2 mg, an antihistamine.